Jump to Topics

Estrogen: hormone of womanhood

Estrogen: hormone of womanhood

Exercising regularly, sleeping well and managing stress can help maintain a good level of estrogen in the body


Estrogen is a class of steroid hormones which regulates the growth, development and physiology of the human reproductive system. It plays an important role in the development and regulation of primary sexual characteristics of women (such as menarche) and secondary sexual characteristics (such as breast development and pubic hair).

Estrogen is essential for every woman, and neither primary nor secondary sexual characteristics will fully develop in its absence, according to Dr Ananatharaman R, consultant endocrinologist at Magna Centres for Obesity, Diabetes and Endocrinology, Bengaluru.

Causes of low estrogen in women

Low levels of estrogen in women may result from premature ovarian failure, certain congenital conditions like Turner syndrome, hypopituitarism (where the pituitary glands do not produce a normal amount of hormones), hypogonadism (when the ovaries or the body’s sex glands produce little or no hormone), thyroid disorders, chemotherapy, extreme exercise and being severely underweight, according to Dr Louis Cojandaraj A, associate professor and research coordinator at Lovely Professional University, Phagwara, Punjab.

Dr Deepti Asthana, senior consultant, obstetrics and gynecology, Fortis Memorial Research Institute, Gurugram, Haryana, tells Happiest Health that menopausal women and girls who have not attained puberty have low levels of estrogen. “Once you attain puberty, there are various causes of low estrogen,” says Dr Asthana. “It could be due to the removal of ovaries, premature menopause, chronic kidney disease and many auto-immune and genetic disorders. Estrogen is also low in conditions such as anorexia nervosa.”

Symptoms of low estrogen in women

Dr Asthana says the symptoms of low estrogen are hot flashes, sweating, weight gain, hair thinning, dry skin, vaginal dryness, irregular menstrual cycle, infertility, mood changes, trouble sleeping, low sex drive and osteoporosis. These symptoms are usually seen in women who have attained menopause.

If low estrogen in reproductive women persists for long, it can lead to bone fragility or fracture; the bone mineral density goes down, making the bones weaker, says Dr Ananatharaman.

Dr Cojandaraj says amenorrhea, headaches and depression are also symptoms of low estrogen.

Causes of high estrogen in women

Dr Cojandaraj says that health conditions such as polycystic ovarian syndrome, endometriosis, uterine fibroids, certain types of cancers and insulin resistance can lead to high estrogen. Other factors include obesity, stress, alcohol consumption and certain medications.

Dr Asthana says these factors, in turn, increase cortisol levels. “Increase in cortisol level depletes the levels of progesterone which balances estrogen,” she says.  

Symptoms of high estrogen

Experts say high levels of estrogen in females can cause symptoms such as irregular periods (light or heavy periods), weight gain, fatigue, uterine fibroids, fibrocystic breast lumps, anxiety, bloating, hair loss, disrupted sleep, bloating and premenstrual syndrome.

In males, symptoms include gynecomastia (enlarged breasts), erectile dysfunction and infertility.


Bacterial infection during pregnancy

Ways to manage stress urinary incontinence

Lifestyle changes

Doctors say that to keep estrogen levels in a healthy range and prevent hormone imbalances, certain lifestyle changes should be adopted:

  • Getting an adequate amount of sleep
  • Managing stress levels
  • Getting the right amount of exercise
  • A healthy diet and practising good eating habits
  • Limiting alcohol intake

Dr Ananathraman says hormone therapy is given to those with severe symptoms.


“To check the level of estrogen, we monitor the menstrual cycle of a female,” says Dr Anantharaman. “A normal menstrual cycle is an indication that the estrogen levels are in control. Estrogen levels are also measured when girls attain late puberty, to check the growth of the uterus (uterine development).”

Estrogen levels differ every day in every woman. The ideal range includes:

  • 30 to 400 pg/mL (picograms per millilitre) for premenopausal women
  • 0 to 30 pg/mL for postmenopausal women

The link between estrogen, progesterone

Progesterone and estrogen are both ovarian hormones. Estrogen helps in the regulation of the menstrual cycle and progesterone prepares the uterus during pregnancy. Estrogen and progesterone play a vital role in the maturation of female secondary sex organs, implantation of ovum and maintenance of pregnancy. Estrogen levels naturally fluctuate during the menstrual cycle along with progesterone.

Estrogen increases the growth of breast cells. Progesterone decreases the rate of multiplication of the breast cells, which helps in the prevention of many breast cancers.

Types of estrogen

  • Estrone – Plays an important role in the reproductive system of females. It is considered the storehouse of estrogen.
  • Estradiol – Controls how the female reproductive cycles of ovulation and menstruation are regulated. Female secondary sexual traits like the growth of the breasts, broadening of the hips and a pattern of fat distribution specific to women are all driven by estradiol. During puberty, maturity and pregnancy, it plays a crucial role in the growth and maintenance of female reproductive structures like the uterus, vagina and mammary glands. Numerous other tissues — such as bone, fat, skin, liver and the brain — are also significantly impacted.
  • Estriol (E3) — Generally undetectable when not pregnant. But a high level of E3 is secreted in the placenta during pregnancy.
  • Estetrol – Produced exclusively in the fetal liver and found only during pregnancy. It is called the native estrogen of fetal life.

Share Your Experience/Comments

Leave a Reply

Your email address will not be published. Required fields are marked *



Physical activity improves the quality as well as duration of sleep. But exercising too close to bedtime is not advisable
While what causes Bell’s palsy is unknown, use of modern medicine along with holistic approaches could offer quick relief
CPR or cardiopulmonary resuscitation is an emergency lifesaving procedure performed when the heart stops beating. According to American Heart Association, immediate CPR can double or triple chances of survival after cardiac arrest. Keeping the blood flow active, even partially, extends the opportunity for a successful resuscitation once trained medical staff arrive on site. It is an important lifesaving first-aid tool that can be performed by anyone.




Opt-in To Our Daily Newsletter

* Please check your Spam folder for the Opt-in confirmation mail
We use cookies to customize your user experience, view our policy here

Your feedback has been submitted successfully.

The Happiest Health team will reach out to you at the earliest